When Sleep Speaks: CAU Research on Metabolic Syndrome
Central Asian University proudly showcases a significant research achievement by Diyora Pulatova, a CAU Medical School graduate. This comprehensive review was authored during her 6th year of medical training and published upon graduation in a Scopus Q2- indexed journal.
The study provides a compelling analysis of how sleep disorders-including insomnia, obstructive sleep apnea, and circadian rhythm disturbances-contribute to the development of metabolic syndrome, a major driver of type 2 diabetes and cardiovascular disease.
By integrating epidemiological, clinical, and experimental evidence, the research reveals how disrupted sleep impacts metabolic health through:
insulin resistance and central obesity
dysregulation of key hormones such as cortisol, leptin, and ghrelin
disturbance of the HPA axis and melatonin pathways
increased risks of hypertension and dyslipidemia
Importantly, the study identifies future research pathways focused on early diagnosis, preventive strategies, and targeted treatments to improve long-term health outcomes.